In extremely-low-birth-weight (ELBW, birth weight of <1000 g) infants, prolonged initial empiric antibiotic therapy should be used with caution. It could cause an increased risk for necrotizing enterocolitis (NEC) or death. Although cultures from normally sterile sites usually do not yield any bacterial agents and the incidence of culture-proven bacterial sepsis is low in this population, ELBW infants admitted to intensive care nurseries usually receive empirical antibiotic treatment in the first postnatal days. A study suggested that cefotaxime for the first 3 postnatal days is associated with higher mortality risk, even for the most preterm infants.
(Pediatrics. 2009;123;58-66).
Showing posts with label nosocomial. Show all posts
Showing posts with label nosocomial. Show all posts
Thursday, January 8, 2009
Friday, January 2, 2009
Universal Screening at Hospital Admission to Reduce Nosocomial Methicillin-resistant Staphylococcus aureus (MRSA) Infection?
A study reported in the March 12 issue of the Journal of the American Medical Association (JAMA. 2008;299:1149-1157, 1190-1192.) concluded that universal screening on hospital admission for methicillin-resistant Staphylococcus aureus (MRSA) infection may not reduce the rate of hospital-acquired infections in surgical patients.
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